Phospho irf3

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August undefined, 2024

WebWestern Blot using Phospho-IRF3 (Ser386) Polyclonal Antibody ( Product # PA5-78025 ). Untreated (–) and treated (+) THP-1 whole cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with Phospho-IRF3 (Ser386) Polyclonal Antibody ( Product # PA5-78025) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody ... WebSep 19, 2013 · IRF3 is a constitutively expressed transcription factor that resides in the cytoplasm and dimerizes and translocates to the nucleus upon phosphorylation ( 6 ). Phosphorylated IRF3 induces IFN-β during viral infection, but may also contribute to inflammatory cytokine response to LPS ( 7 ).

Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in

WebDetect and quantitate cellular phospho-IRF3 (Ser386) using a homogeneous AlphaLISA® SureFire® Ultra™ assay. We are now two standalone organizations Life Sciences & … WebIRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response. In unstimulated cells, IRF-3 is present in the cytoplasm. … bisect sds

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WebPhospho-IRF3 (S386) ELISA Kit (ab279833) is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in human cell lysates. By determining phosphorylated IRF3 protein in your experimental model system, you can verify pathway activation in your cell lysates. WebPhosphorylated IRF3 forms a dimer that translocates to the nucleus and induces type I IFNs and other cytokines. After activation by STING, TBK1 and its homolog IκB kinase epsilon (IKKε) can both lead to activation of the IKK complex, which then activates the transcription factor nuclear factor κB (NF-κB) (11, 12). WebJul 7, 2024 · Phospho-S365 acts as a docking site for IRF3, a transcription factor that is phosphorylated and activated by TBK1, leading to transcriptional induction of type I … dark chocolate feves

Phospho-IRF3 (S386) ELISA Kit (ab279833) Abcam

Anti-phospho IRF3 (ser386) Antibody - Sigma-Aldrich

WebInvitrogen Anti-Phospho-IRF3 (Ser385) Polyclonal, Catalog # PA5-36775. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC … WebSep 1, 2024 · To systematically search for the phosphorylation sites on IRF3 in vivo, we carried out tandem affinity purification of recombinant double-tagged IRF3 expressed in HEK293 cells, coupling with mass spectrometric analysis (Fig. 1 A and B). Several phospho-peptides were identified with different color highlighted in the whole amino acid sequence … bisect_right pythonWebAll lanes : Anti-IRF3 (phospho S386) antibody [EPR2346] (ab76493) at 0.2 µg/ml (purified) Lane 1 : MCF7 (Human breast adenocarcinoma epithelial cell) whole cell lysates Lane 2 : … bisect search

"WebPhospho-IRF3 (S386) and Total IRF3 (S386) ELISA Kit (ab279834) is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in human cell lysates. By determining phosphorylated IRF3 protein in your experimental model system, you can verify pathway activation in your cell lysates. " - Phospho irf3

Phospho irf3

US20240107770A1 METHOD OF ENHANCING IMMUNOTHERAPY …

WebNational Center for Biotechnology Information Web55. A method of treating, inhibiting, reducing, ameliorating, and/or preventing a cancer and or metastasis in a subject comprising administering to a subject an adoptive immunothe

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WebSep 19, 2013 · IRF3 is a constitutively expressed transcription factor that resides in the cytoplasm and dimerizes and translocates to the nucleus upon phosphorylation ( 6 ). … WebPrimary Anti-IRF3 (phospho S386) antibody [EPR2346] - BSA and Azide free (ab182859) Protein Recombinant Human IRF3 protein (ab205216) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718) View more associated products Overview Product name Anti-IRF3 (phospho S396) antibody See all IRF3 primary antibodies Description

WebApr 28, 2024 · Immunoblotting experiments indicated that phosphorylation of IRF3 S386, which is a hallmark of cGAS-mediated activation of downstream events 21, ... (Histone H3 phospho S10) and cyclin B was used ... IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 is found …

WebThe phospho-IRF3 cell based assay kit conveniently and accurately quantifies phosphorylated IRF3 at Ser386. In viral infected cells, phosphorylation of transcription … WebJun 1, 2024 · IRF-3 Antibody (SL-12) is a mouse monoclonal IgG 1 κ IRF-3 antibody, cited in 73 publications, provided at 200 µg/ml raised against recombinant IRF-3 fusion protein corresponding to human IRF-3 (amino acids 56-427) IRF-3 Antibody (SL-12) is recommended for detection of IRF-3 of mouse, rat and human origin by WB, IP, IF and IHC …

WebWestern blot analysis of extracts of NIH/3T3 cells, using Phospho-IRF3-S396 antibody (AP0623) at 1:1000 dilution.NIH/3T3 cells were treated by Calyculin A (100 nM) at 37℃ for 30 minutes after serum-starvation overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane.

WebC920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3 Host Species Rabbit bisect scipyWeb环保商城会员企业上海邦景实业有限公司提供杂交瘤细胞；tbcd6规格, 细胞名称杂交瘤细胞；tbcd6规格形态特性淋巴母细胞样生长特性半贴壁生长特征特性该细胞属保藏，其特征特性尚未公开。培养条件 dark chocolate flipz ukWeb"Phospho-IRF3 (Ser396) antibodies" comparison At Proteintech, we pride ourselves on our antibody quality, customer service and transparency. As such, we are comparing our antibodies with other vendors, enabling easy identification and comparisons of key data to help you choose the suitable antibody for your needs. dark chocolate female hormonesWebApr 13, 2024 · Antibodies. The following antibodies were used: mouse monoclonal antibodies to α-tubulin (Santa Cruz, sc23948), GAPDH (Santa Cruz, sc32233), phospho-H2A.X (Ser139) (EMD Millipore, 05-636), anti ... bisect server decompress option not thereWebApr 23, 2024 · We focused on the phosphorylation of IRF3, which is a downstream factor of the cGAS pathway . As shown in Figure 2A, the expression of phosphorylated-IRF3 (p-IRF3) was increased in HNSCC cells after X-ray irradiation, and cGAS knockdown suppressed the radiation-increased p-IRF3. These results suggest that ionizing radiation activates IRF3 ... bisects definition mathWebAnti-IRF3 (phospho S386) antibody [EPR2346] (ab76493) Research with confidence – consistent and reproducible results with every batch Long-term and scalable supply – powered by recombinant technology for fast … bisect shape blenderWeb0.1ml Phospho-IRF3 (Ser396) 磷酸化干扰素调节因子3 130428-200503 0.2ml IRAK4 白介素-1受体相关激酶4抗体 130429-200203 0.1ml phospho-IRAK4(Thr345) 磷酸化白介素-1受体相关激酶4抗体 130430-200305 0.2ml IL-1RA 白介素-1受体拮抗剂抗体 0431-9501 bisect right triangle